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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human AQP3 HGNC:636 (HGNC)
360 (Entrez Gene)
600170 (OMIM)
Aquaporin 3 (MyGene.info)
HGNC homology
Chr9 p13.3 Chr9:33441154-33447633 (-)
Q92482 (UniProt | EBI)
NM_001318144 (RefSeq)
mouse Aqp3 MGI:1333777 (MGI)
11828 (Entrez Gene)
Gene Tree
HGNC homology
Chr4 20.94 cM Chr4:41092724-41098183 (-)
nephrogenic diabetes insipidus
11828 (NCBI Gene Model)
Q8R2N1 (UniProt | EBI)
NM_016689 (RefSeq)
rat Aqp3 65133 (Entrez Gene)
Chr5 q22 P47862 (UniProt | EBI)
NM_031703 (RefSeq)
chimpanzee AQP3 465045 (Entrez Gene)
Chr9 XP_016816223 (RefSeq)
cattle AQP3 780866 (Entrez Gene)
Chr8 Q08DE6 (UniProt | EBI)
NM_001079794 (RefSeq)
dog AQP3 611792 (Entrez Gene)
Chr11 XP_022281211 (RefSeq)
chicken AQP3 426894 (Entrez Gene)
ChrZ XP_424500 (RefSeq)
zebrafish aqp3a 406777 (Entrez Gene)
Chr5 NP_998633 (RefSeq)
NM_213468 (RefSeq)
aqp3b 568049 (Entrez Gene)
Chr21 NP_001159593 (RefSeq)
NM_001166121 (RefSeq)
frog, western clawed aqp3 549599 (Entrez Gene)
Chr1 NP_001016845 (RefSeq)
NM_001016845 (RefSeq)
macaque, rhesus AQP3 702721 (Entrez Gene)
Chr15 NP_001244972 (RefSeq)
NM_001258043 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory