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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human NRXN1 HGNC:8008 (HGNC)
9378 (Entrez Gene)
600565 (OMIM)
HGNC homology
Chr2 p16.3 Chr2:49918505-51032536 (-)
Chromosome 2p16.3 Deletion Syndrome
Pitt-Hopkins-Like Syndrome 2; PTHSL2
Q9ULB1 (UniProt | EBI)
NM_138735 (RefSeq)
mouse Nrxn1 MGI:1096391 (MGI)
18189 (Entrez Gene)
Gene Tree
Chr17 59.73 cM Chr17:90033631-91093071 (-)
Schizophrenia; SCZD
OTTMUSG00000034567 (VEGA)
OTTMUSP00000047783 (VEGA)
OTTMUST00000087771 (VEGA)
rat Nrxn1 60391 (Entrez Gene)
Chr6 q12 Q63373 (UniProt | EBI)
NM_021767 (RefSeq)
chimpanzee NRXN1 459224 (Entrez Gene)
Chr2A XP_009440733 (RefSeq)
rhesus macaque NRXN1 619185 (Entrez Gene)
Chr13 XP_001114208 (RefSeq)
cattle NRXN1 281950 (Entrez Gene)
Chr11 Q28146 (UniProt | EBI)
NM_174404 (RefSeq)
dog NRXN1 474589 (Entrez Gene)
Chr10 XP_013972997 (RefSeq)
chicken NRXN1 395398 (Entrez Gene)
Chr3 Q9DDD0 (UniProt | EBI)
NM_001198975 (RefSeq)
western clawed frog nrxn1 100127647 (Entrez Gene)
ChrUN XP_012819330 (RefSeq)
zebrafish nrxn1a 565531 (Entrez Gene)
Chr12 A1XQX0 (UniProt | EBI)
NM_001080021 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.01
The Jackson Laboratory