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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
210

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MSH2 HGNC:7325 (HGNC)
4436 (Entrez Gene)
609309 (OMIM)
Chr2 p21 Chr2:47403067-47512577 (+)
GRCh38
Lynch Syndrome I
Mismatch Repair Cancer Syndrome; MMRCS
Muir-Torre Syndrome; MRTES
P43246 (UniProt | EBI)
NM_000251 (RefSeq)
mouse Msh2 MGI:101816 (MGI)
17685 (Entrez Gene)
Gene Tree
VISTA-Point
Chr17 57.87 cM Chr17:87672330-87723713 (+)
GRCm38
Lynch Syndrome I
OTTMUSG00000038134 (VEGA)
OTTMUSP00000055147 (VEGA)
OTTMUST00000098216 (VEGA)
rat Msh2 81709 (Entrez Gene)
Chr6 q12 P54275 (UniProt | EBI)
NM_031058 (RefSeq)
cattle MSH2 533115 (Entrez Gene)
Chr11 Q3MHE4 (UniProt | EBI)
NM_001034584 (RefSeq)
dog MSH2 494002 (Entrez Gene)
Chr10 XP_538482 (RefSeq)
chicken MSH2 378799 (Entrez Gene)
Chr3 XP_426110 (RefSeq)
western clawed frog msh2 100380043 (Entrez Gene)
ChrUN XP_002935427 (RefSeq)
zebrafish msh2 406845 (Entrez Gene)
Chr12 NP_998689 (RefSeq)
NM_213524 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory