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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human NPHS1 HGNC:7908 (HGNC)
4868 (Entrez Gene)
602716 (OMIM)
Nephrin (MyGene.info)
HGNC homology
Chr19 q13.12 Chr19:35825372-35851993 (-)
nephrotic syndrome type 1
O60500 (UniProt | EBI)
NM_004646 (RefSeq)
mouse Nphs1 MGI:1859637 (MGI)
54631 (Entrez Gene)
Gene Tree
HGNC homology
Chr7 18.36 cM Chr7:30458315-30487223 (+)
nephrotic syndrome
ENSMUSG00000006649 (Ensembl Gene Model)
ENSMUSP00000006825 (Ensembl)
ENSMUST00000006825 (Ensembl)
rat Nphs1 64563 (Entrez Gene)
Chr1 q21 Q9R044 (UniProt | EBI)
NM_022628 (RefSeq)
chimpanzee NPHS1 468841 (Entrez Gene)
Chr19 XP_016791215 (RefSeq)
cattle NPHS1 519706 (Entrez Gene)
Chr18 NP_001179441 (RefSeq)
NM_001192512 (RefSeq)
dog NPHS1 484571 (Entrez Gene)
Chr1 XP_022259248 (RefSeq)
zebrafish nphs1 692352 (Entrez Gene)
Chr15 NP_001035777 (RefSeq)
NM_001040687 (RefSeq)
frog, western clawed nphs1 100494620 (Entrez Gene)
Chr7 XP_031761552 (RefSeq)
macaque, rhesus NPHS1 718929 (Entrez Gene)
Chr19 XP_028695879 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory