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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LRP2 HGNC:6694 (HGNC)
4036 (Entrez Gene)
600073 (OMIM)
HGNC homology
Chr2 q31.1 Chr2:169127109-169362613 (-)
Donnai-Barrow Syndrome
P98164 (UniProt | EBI)
NM_004525 (RefSeq)
mouse Lrp2 MGI:95794 (MGI)
14725 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 40.74 cM Chr2:69424340-69586065 (-)
Donnai-Barrow Syndrome
OTTMUSG00000012988 (VEGA)
OTTMUSP00000014001 (VEGA)
OTTMUST00000031293 (VEGA)
rat Lrp2 29216 (Entrez Gene)
Chr3 q21 P98158 (UniProt | EBI)
NM_030827 (RefSeq)
chimpanzee LRP2 459713 (Entrez Gene)
Chr2B XP_009441921 (RefSeq)
rhesus macaque LRP2 705786 (Entrez Gene)
Chr12 XP_001104179 (RefSeq)
cattle LRP2 100337021 (Entrez Gene)
Chr2 XP_010824735 (RefSeq)
dog LRP2 478781 (Entrez Gene)
Chr36 XP_005640341 (RefSeq)
chicken LRP2 424168 (Entrez Gene)
Chr7 XP_004942820 (RefSeq)
western clawed frog lrp2 100489914 (Entrez Gene)
ChrUN XP_012826499 (RefSeq)
zebrafish lrp2a 568184 (Entrez Gene)
Chr9 NP_001181916 (RefSeq)
NM_001194987 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.0
The Jackson Laboratory