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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human GPC3 HGNC:4451 (HGNC)
2719 (Entrez Gene)
300037 (OMIM)
Glypican 3 (MyGene.info)
HGNC homology
ChrX q26.2 ChrX:133535745-133985646 (-)
Simpson-Golabi-Behmel syndrome
P51654 (UniProt | EBI)
NM_001164617 (RefSeq)
mouse Gpc3 MGI:104903 (MGI)
14734 (Entrez Gene)
Gene Tree
HGNC homology
ChrX 28.74 cM ChrX:52272426-52613950 (-)
Simpson-Golabi-Behmel syndrome
OTTMUSG00000017333 (VEGA)
OTTMUSP00000018969 (VEGA)
OTTMUST00000042115 (VEGA)
rat Gpc3 25236 (Entrez Gene)
ChrX q36 P13265 (UniProt | EBI)
NM_012774 (RefSeq)
chimpanzee GPC3 465866 (Entrez Gene)
ChrX A5A6P7 (UniProt | EBI)
NM_001135737 (RefSeq)
cattle GPC3 615239 (Entrez Gene)
ChrX NP_001030540 (RefSeq)
NM_001035463 (RefSeq)
dog GPC3 481056 (Entrez Gene)
ChrX XP_538178 (RefSeq)
chicken GPC3 770863 (Entrez Gene)
Chr4 XP_015134145 (RefSeq)
zebrafish gpc3 387365 (Entrez Gene)
Chr14 NP_001292547 (RefSeq)
NM_001305618 (RefSeq)
frog, western clawed gpc3 100135027 (Entrez Gene)
Chr8 XP_002932665 (RefSeq)
macaque, rhesus GPC3 706773 (Entrez Gene)
ChrX XP_014983699 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory