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Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LGR5 HGNC:4504 (HGNC)
8549 (Entrez Gene)
606667 (OMIM)
Chr12 q22-q23 Chr12:71439154-71586310 (+)
O75473 (UniProt | EBI)
NM_003667 (RefSeq)
mouse Lgr5 MGI:1341817 (MGI)
14160 (Entrez Gene)
Gene Tree
Chr10 63.51 cM Chr10:115450311-115587780 (-)
OTTMUSG00000020836 (VEGA)
OTTMUSP00000022795 (VEGA)
OTTMUST00000049259 (VEGA)
rat Lgr5 299802 (Entrez Gene)
Chr7 q22 D4AC13 (UniProt | EBI)
NM_001106784 (RefSeq)
chimpanzee LGR5 743138 (Entrez Gene)
Chr12 XP_003313909 (RefSeq)
rhesus macaque LGR5 718661 (Entrez Gene)
Chr11 XP_001117492 (RefSeq)
cattle LGR5 520189 (Entrez Gene)
Chr5 F1MT22 (UniProt | EBI)
NM_001192520 (RefSeq)
chicken LGR5 427867 (Entrez Gene)
Chr1 XP_425441 (RefSeq)
western clawed frog lgr5 100486389 (Entrez Gene)
ChrUN F7D3V9 (UniProt | EBI)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory