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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 67, Dec 12, 2012)
208

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MLH1 HGNC:7127 (HGNC)
4292 (Entrez Gene)
120436 (OMIM)
Chr3 p21.3 Chr3:36993350-37050846 (+)
GRCh38
Colorectal Cancer, Hereditary Nonpolyposis, Type 2; HNPCC2
Mismatch Repair Cancer Syndrome; MMRCS
Muir-Torre Syndrome; MRTES
P40692 (UniProt | EBI)
NM_000249 (RefSeq)
mouse Mlh1 MGI:101938 (MGI)
17350 (Entrez Gene)
Gene Tree
VISTA-Point
Chr9 60.92 cM Chr9:111228228-111271608 (-)
GRCm38
Colorectal Cancer, Hereditary Nonpolyposis, Type 2; HNPCC2
OTTMUSG00000031784 (VEGA)
OTTMUSP00000041918 (VEGA)
OTTMUST00000078764 (VEGA)
rat Mlh1 81685 (Entrez Gene)
Chr8 q32 P97679 (UniProt | EBI)
NM_031053 (RefSeq)
chimpanzee MLH1 747104 (Entrez Gene)
Chr3 XP_001170253 (RefSeq)
cattle MLH1 533652 (Entrez Gene)
Chr22 NP_001069462 (RefSeq)
NM_001075994 (RefSeq)
dog MLH1 477019 (Entrez Gene)
Chr23 XP_534219 (RefSeq)
chicken MLH1 420729 (Entrez Gene)
Chr2 XP_418828 (RefSeq)
zebrafish mlh1 393632 (Entrez Gene)
Chr13 NP_956953 (RefSeq)
NM_200659 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory