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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TYK2 HGNC:12440 (HGNC)
7297 (Entrez Gene)
176941 (OMIM)
Tyrosine kinase 2 (MyGene.info)
HGNC homology
Chr19 p13.2 Chr19:10350528-10380572 (-)
P29597 (UniProt | EBI)
NM_003331 (RefSeq)
mouse Tyk2 MGI:1929470 (MGI)
54721 (Entrez Gene)
Gene Tree
HGNC homology
Chr9 7.71 cM Chr9:21104068-21131243 (-)
ENSMUSG00000032175 (Ensembl Gene Model)
ENSMUSP00000150354 (Ensembl)
ENSMUST00000216874 (Ensembl)
rat Tyk2 100361294 (Entrez Gene)
Chr8 NP_001244276 (RefSeq)
NM_001257347 (RefSeq)
chimpanzee TYK2 455703 (Entrez Gene)
Chr19 XP_024207007 (RefSeq)
cattle TYK2 512484 (Entrez Gene)
Chr7 NP_001107236 (RefSeq)
NM_001113764 (RefSeq)
dog TYK2 476714 (Entrez Gene)
Chr20 XP_022262766 (RefSeq)
zebrafish tyk2 100536675 (Entrez Gene)
Chr3 XP_003198201 (RefSeq)
frog, western clawed tyk2 100489432 (Entrez Gene)
Chr3 XP_004918871 (RefSeq)
macaque, rhesus TYK2 574130 (Entrez Gene)
Chr19 XP_014978338 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory