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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TRHR HGNC:12299 (HGNC)
7201 (Entrez Gene)
188545 (OMIM)
HGNC homology
Chr8 q23.1 Chr8:109085745-109119785 (+)
P34981 (UniProt | EBI)
NM_003301 (RefSeq)
mouse Trhr MGI:98824 (MGI)
22045 (Entrez Gene)
Gene Tree
HGNC homology
Chr15 16.82 cM Chr15:44196135-44235912 (+)
congenital hypothyroidism
ENSMUSG00000038760 (Ensembl Gene Model)
ENSMUSP00000105918 (Ensembl)
ENSMUST00000110289 (Ensembl)
rat Trhr 25570 (Entrez Gene)
Chr7 q31 Q01717 (UniProt | EBI)
NM_013047 (RefSeq)
chimpanzee TRHR 472842 (Entrez Gene)
Chr8 XP_009454079 (RefSeq)
cattle TRHR 281549 (Entrez Gene)
Chr14 O46639 (UniProt | EBI)
NM_174203 (RefSeq)
dog TRHR 482007 (Entrez Gene)
Chr13 XP_539128 (RefSeq)
chicken TRHR 395770 (Entrez Gene)
Chr2 O93603 (UniProt | EBI)
NM_204930 (RefSeq)
zebrafish trhra 558878 (Entrez Gene)
Chr16 XP_687246 (RefSeq)
trhrb 569382 (Entrez Gene)
Chr19 NP_001108160 (RefSeq)
NM_001114688 (RefSeq)
frog, western clawed trhr 100492507 (Entrez Gene)
Chr6 XP_002938958 (RefSeq)
macaque, rhesus TRHR 698511 (Entrez Gene)
Chr8 XP_001091307 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory