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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TLR5 HGNC:11851 (HGNC)
7100 (Entrez Gene)
603031 (OMIM)
TLR 5 (MyGene.info)
HGNC homology
Chr1 q41 Chr1:223108401-223143282 (-)
Legionnaires' disease
systemic lupus erythematosus
O60602 (UniProt | EBI)
NM_003268 (RefSeq)
mouse Tlr5 MGI:1858171 (MGI)
53791 (Entrez Gene)
Gene Tree
HGNC homology
Chr1 86.12 cM Chr1:182954788-182976044 (+)
ENSMUSG00000079164 (Ensembl Gene Model)
ENSMUSP00000106625 (Ensembl)
ENSMUST00000110997 (Ensembl)
rat Tlr5 289337 (Entrez Gene)
Chr13 q26 NP_001139300 (RefSeq)
NM_001145828 (RefSeq)
chimpanzee TLR5 457762 (Entrez Gene)
Chr1 NP_001123934 (RefSeq)
NM_001130462 (RefSeq)
cattle TLR5 444870 (Entrez Gene)
Chr16 NP_001035591 (RefSeq)
NM_001040501 (RefSeq)
dog TLR5 488605 (Entrez Gene)
Chr38 NP_001184105 (RefSeq)
NM_001197176 (RefSeq)
chicken TLR5 554217 (Entrez Gene)
Chr3 NP_001019757 (RefSeq)
NM_001024586 (RefSeq)
zebrafish tlr5a 403138 (Entrez Gene)
Chr20 XP_001919052 (RefSeq)
tlr5b 403139 (Entrez Gene)
Chr20 NP_001124067 (RefSeq)
NM_001130595 (RefSeq)
frog, western clawed tlr5 100496647 (Entrez Gene)
Chr5 XP_002940742 (RefSeq)
macaque, rhesus TLR5 574328 (Entrez Gene)
Chr1 NP_001123901 (RefSeq)
NM_001130429 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory