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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PROX1 HGNC:9459 (HGNC)
5629 (Entrez Gene)
601546 (OMIM)
HGNC homology
Chr1 q41 Chr1:213983226-214041510 (+)
Q92786 (UniProt | EBI)
NM_002763 (RefSeq)
mouse Prox1 MGI:97772 (MGI)
19130 (Entrez Gene)
Gene Tree
Chr1 95.85 cM Chr1:190118035-190170714 (-)
Lymphangiectasia, Pulmonary, Congenital; CPL
OTTMUSG00000040162 (VEGA)
OTTMUSP00000058419 (VEGA)
OTTMUST00000104400 (VEGA)
rat Prox1 305066 (Entrez Gene)
Chr13 q27 NP_001100671 (RefSeq)
NM_001107201 (RefSeq)
chimpanzee PROX1 457728 (Entrez Gene)
Chr1 XP_009439742 (RefSeq)
rhesus macaque PROX1 709465 (Entrez Gene)
Chr1 NP_001247802 (RefSeq)
NM_001260873 (RefSeq)
cattle PROX1 515324 (Entrez Gene)
Chr16 NP_001180161 (RefSeq)
NM_001193232 (RefSeq)
dog PROX1 490291 (Entrez Gene)
Chr7 XP_005622418 (RefSeq)
chicken PROX1 395802 (Entrez Gene)
Chr3 Q91018 (UniProt | EBI)
NM_001005616 (RefSeq)
western clawed frog prox1 100134995 (Entrez Gene)
ChrUN XP_002934750 (RefSeq)
zebrafish prox1a 30679 (Entrez Gene)
Chr17 NP_571480 (RefSeq)
NM_131405 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.0
The Jackson Laboratory