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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 67, Dec 12, 2012)
20584

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PITX1 HGNC:9004 (HGNC)
5307 (Entrez Gene)
602149 (OMIM)
Chr5 q31.1 Chr5:135027734-135034274 (-)
GRCh38
Clubfoot, Congenital, with or without Deficiency of Long Bones and/or Mirror-Image Polydactyly; CCF
Liebenberg Syndrome; LBNBG
P78337 (UniProt | EBI)
NM_002653 (RefSeq)
mouse Pitx1 MGI:107374 (MGI)
18740 (Entrez Gene)
Gene Tree
VISTA-Point
Chr13 30.06 cM Chr13:55825051-55836192 (-)
GRCm38
Clubfoot, Congenital, with or without Deficiency of Long Bones and/or Mirror-Image Polydactyly; CCF
OTTMUSG00000037718 (VEGA)
OTTMUSP00000054634 (VEGA)
OTTMUST00000097411 (VEGA)
rat Pitx1 113983 (Entrez Gene)
Chr17 p14 Q99NA7 (UniProt | EBI)
NM_053624 (RefSeq)
chimpanzee PITX1 462072 (Entrez Gene)
Chr5 XP_001168135 (RefSeq)
rhesus macaque PITX1 711666 (Entrez Gene)
Chr6 XP_001110089 (RefSeq)
cattle PITX1 508754 (Entrez Gene)
Chr7 NP_001192229 (RefSeq)
NM_001205300 (RefSeq)
dog PITX1 481513 (Entrez Gene)
Chr11 XP_005626613 (RefSeq)
chicken PITX1 374201 (Entrez Gene)
Chr13 P56673 (UniProt | EBI)
NM_001167684 (RefSeq)
zebrafish pitx1 678598 (Entrez Gene)
Chr21 NP_001035436 (RefSeq)
NM_001040346 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory