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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ELANE HGNC:3309 (HGNC)
1991 (Entrez Gene)
130130 (OMIM)
Neutrophil elastase (MyGene.info)
HGNC homology
Chr19 p13.3 Chr19:850997-856250 (+)
cyclic hematopoiesis
severe congenital neutropenia 1
P08246 (UniProt | EBI)
NM_001972 (RefSeq)
mouse Elane MGI:2679229 (MGI)
50701 (Entrez Gene)
Gene Tree
HGNC homology
Chr10 39.72 cM Chr10:79886312-79888216 (+)
50701 (NCBI Gene Model)
Q3UP87 (UniProt | EBI)
NM_015779 (RefSeq)
rat Elane 299606 (Entrez Gene)
Chr7 q11 NP_001100237 (RefSeq)
NM_001106767 (RefSeq)
chimpanzee ELANE 749897 (Entrez Gene)
cattle ELANE 100126050 (Entrez Gene)
Chr7 NP_001099123 (RefSeq)
NM_001105653 (RefSeq)
dog ELANE 442980 (Entrez Gene)
Chr20 NP_001003378 (RefSeq)
NM_001003378 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory