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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CHRNA2 HGNC:1956 (HGNC)
1135 (Entrez Gene)
118502 (OMIM)
CHRNA2 (MyGene.info)
HGNC homology
Chr8 p21.2 Chr8:27459761-27479296 (-)
autosomal dominant nocturnal frontal lobe epilepsy 4
Q15822 (UniProt | EBI)
NM_000742 (RefSeq)
mouse Chrna2 MGI:87886 (MGI)
110902 (Entrez Gene)
Gene Tree
HGNC homology
Chr14 34.36 cM Chr14:66135039-66152948 (+)
OTTMUSG00000039812 (VEGA)
OTTMUSP00000074647 (VEGA)
OTTMUST00000143175 (VEGA)
rat Chrna2 170945 (Entrez Gene)
Chr15 p12 P12389 (UniProt | EBI)
NM_133420 (RefSeq)
chimpanzee CHRNA2 472725 (Entrez Gene)
Chr8 Q5IS52 (UniProt | EBI)
NM_001033935 (RefSeq)
cattle CHRNA2 531838 (Entrez Gene)
Chr8 NP_001179639 (RefSeq)
NM_001192710 (RefSeq)
dog CHRNA2 486101 (Entrez Gene)
Chr25 XP_005635946 (RefSeq)
chicken CHRNA2 395607 (Entrez Gene)
Chr3 P09480 (UniProt | EBI)
NM_204815 (RefSeq)
frog, western clawed chrna2 100495873 (Entrez Gene)
Chr5 XP_004914998 (RefSeq)
macaque, rhesus CHRNA2 712868 (Entrez Gene)
Chr8 XP_015000511 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory