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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CA4 HGNC:1375 (HGNC)
762 (Entrez Gene)
114760 (OMIM)
Carbonic anhydrase 4 (MyGene.info)
HGNC homology
Chr17 q23.1 Chr17:60149941-60178118 (+)
retinitis pigmentosa 17
P22748 (UniProt | EBI)
NM_000717 (RefSeq)
mouse Car4 MGI:1096574 (MGI)
12351 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 51.34 cM Chr11:84957786-84966044 (+)
OTTMUSG00000001034 (VEGA)
OTTMUSP00000001000 (VEGA)
OTTMUST00000002065 (VEGA)
rat Car4 29242 (Entrez Gene)
Chr10 q26 P48284 (UniProt | EBI)
NM_019174 (RefSeq)
chimpanzee CA4 454807 (Entrez Gene)
Chr17 XP_009431264 (RefSeq)
cattle CA4 280741 (Entrez Gene)
Chr19 Q95323 (UniProt | EBI)
NM_173897 (RefSeq)
dog CA4 480591 (Entrez Gene)
Chr9 XP_537711 (RefSeq)
chicken CA4 417647 (Entrez Gene)
Chr19 XP_415893 (RefSeq)
zebrafish ca4a 555196 (Entrez Gene)
Chr5 NP_001107879 (RefSeq)
NM_001114407 (RefSeq)
ca4b 553246 (Entrez Gene)
Chr15 NP_001159683 (RefSeq)
NM_001166211 (RefSeq)
ca4c 407683 (Entrez Gene)
Chr21 XP_003200928 (RefSeq)
frog, western clawed ca4 100489625 (Entrez Gene)
Chr2 XP_002933882 (RefSeq)
macaque, rhesus CA4 716919 (Entrez Gene)
Chr16 XP_001107970 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory