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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 67, Dec 12, 2012)
20146

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human HEXA HGNC:4878 (HGNC)
3073 (Entrez Gene)
606869 (OMIM)
Chr15 q24.1 Chr15:72343437-72376179 (-)
GRCh38
Tay-Sachs Disease; TSD
P06865 (UniProt | EBI)
NM_000520 (RefSeq)
mouse Hexa MGI:96073 (MGI)
15211 (Entrez Gene)
Gene Tree
VISTA-Point
Chr9 32.02 cM Chr9:59539667-59565105 (+)
GRCm38
Tay-Sachs Disease; TSD
15211 (NCBI Gene Model)
P29416 (UniProt | EBI)
NM_010421 (RefSeq)
rat Hexa 300757 (Entrez Gene)
Chr8 q24 Q641X3 (UniProt | EBI)
NM_001004443 (RefSeq)
chimpanzee HEXA 748732 (Entrez Gene)
Chr15 XP_001175122 (RefSeq)
rhesus macaque HEXA 698251 (Entrez Gene)
Chr7 NP_001248458 (RefSeq)
NM_001261529 (RefSeq)
dog HEXA 487633 (Entrez Gene)
Chr30 XP_544758 (RefSeq)
chicken HEXA 415320 (Entrez Gene)
Chr10 NP_001025561 (RefSeq)
NM_001030390 (RefSeq)
zebrafish zgc:112084 550460 (Entrez Gene)
Chr25 NP_001017763 (RefSeq)
NM_001017763 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory