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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human HEXA HGNC:4878 (HGNC)
3073 (Entrez Gene)
606869 (OMIM)
HEXA (MyGene.info)
HGNC homology
Chr15 q23 Chr15:72343435-72376473 (-)
Tay-Sachs disease
P06865 (UniProt | EBI)
NM_000520 (RefSeq)
mouse Hexa MGI:96073 (MGI)
15211 (Entrez Gene)
Gene Tree
HGNC homology
Chr9 32.02 cM Chr9:59539545-59565109 (+)
Tay-Sachs disease
15211 (NCBI Gene Model)
P29416 (UniProt | EBI)
NM_010421 (RefSeq)
rat Hexa 300757 (Entrez Gene)
Chr8 q24 Q641X3 (UniProt | EBI)
NM_001004443 (RefSeq)
chimpanzee CELF6 748732 (Entrez Gene)
Chr15 XP_016782630 (RefSeq)
cattle HEXA 504468 (Entrez Gene)
Chr10 Q0V8R6 (UniProt | EBI)
NM_001075164 (RefSeq)
dog HEXA 487633 (Entrez Gene)
Chr30 XP_013965054 (RefSeq)
chicken HEXA 415320 (Entrez Gene)
Chr10 NP_001025561 (RefSeq)
NM_001030390 (RefSeq)
zebrafish hexa 550460 (Entrez Gene)
Chr25 NP_001017763 (RefSeq)
NM_001017763 (RefSeq)
macaque, rhesus HEXA 698251 (Entrez Gene)
Chr7 NP_001248458 (RefSeq)
NM_001261529 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory