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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human AQP2 HGNC:634 (HGNC)
359 (Entrez Gene)
107777 (OMIM)
Aquaporin 2 (MyGene.info)
HGNC homology
Chr12 q13.12 Chr12:49950741-49958881 (+)
nephrogenic diabetes insipidus
P41181 (UniProt | EBI)
NM_000486 (RefSeq)
mouse Aqp2 MGI:1096865 (MGI)
11827 (Entrez Gene)
Gene Tree
HGNC homology
Chr15 56.13 cM Chr15:99579056-99584545 (+)
nephrogenic diabetes insipidus
11827 (NCBI Gene Model)
P56402 (UniProt | EBI)
NM_009699 (RefSeq)
rat Aqp2 25386 (Entrez Gene)
Chr7 P34080 (UniProt | EBI)
NM_012909 (RefSeq)
chimpanzee AQP2 451886 (Entrez Gene)
Chr12 XP_016778931 (RefSeq)
cattle AQP2 539870 (Entrez Gene)
Chr5 P79099 (UniProt | EBI)
NM_001101199 (RefSeq)
dog AQP2 486552 (Entrez Gene)
Chr27 P79144 (UniProt | EBI)
NM_001313833 (RefSeq)
chicken AQP2 431304 (Entrez Gene)
Chr33 NP_001279001 (RefSeq)
NM_001292072 (RefSeq)
frog, western clawed aqp2 548466 (Entrez Gene)
Chr2 NP_001015749 (RefSeq)
NM_001015749 (RefSeq)
macaque, rhesus AQP2 711719 (Entrez Gene)
Chr11 NP_001181417 (RefSeq)
NM_001194488 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory