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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human RPE65 HGNC:10294 (HGNC)
6121 (Entrez Gene)
180069 (OMIM)
RPE65 (MyGene.info)
HGNC homology
Chr1 p31.3 Chr1:68428822-68450322 (-)
Leber congenital amaurosis 2
retinitis pigmentosa 20
Q16518 (UniProt | EBI)
NM_000329 (RefSeq)
mouse Rpe65 MGI:98001 (MGI)
19892 (Entrez Gene)
Gene Tree
HGNC homology
Chr3 82.52 cM Chr3:159599175-159625321 (+)
Leber congenital amaurosis 2
retinitis pigmentosa 20
OTTMUSG00000052823 (VEGA)
OTTMUSP00000070514 (VEGA)
OTTMUST00000132202 (VEGA)
rat Rpe65 89826 (Entrez Gene)
Chr2 q45 O70276 (UniProt | EBI)
NM_053562 (RefSeq)
chimpanzee RPE65 744567 (Entrez Gene)
Chr1 XP_016776129 (RefSeq)
cattle RPE65 282043 (Entrez Gene)
Chr3 Q28175 (UniProt | EBI)
NM_174453 (RefSeq)
dog RPE65 403803 (Entrez Gene)
Chr6 Q9TVB8 (UniProt | EBI)
NM_001003176 (RefSeq)
chicken RPE65 395700 (Entrez Gene)
Chr8 Q9YGX2 (UniProt | EBI)
NM_204884 (RefSeq)
zebrafish rpe65a 393724 (Entrez Gene)
Chr2 Q6PBW5 (UniProt | EBI)
NM_200751 (RefSeq)
rpe65b 100002865 (Entrez Gene)
Chr8 A9C3R9 (UniProt | EBI)
NM_001089433 (RefSeq)
rpe65c 100004076 (Entrez Gene)
Chr8 A9C3R8 (UniProt | EBI)
NM_001113653 (RefSeq)
frog, western clawed rpe65 100145692 (Entrez Gene)
Chr4 NP_001120538 (RefSeq)
NM_001127066 (RefSeq)
macaque, rhesus RPE65 701764 (Entrez Gene)
Chr1 XP_014997610 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory