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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
20103

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SERPINA1 HGNC:8941 (HGNC)
5265 (Entrez Gene)
107400 (OMIM)
Chr14 q32.1 Chr14:94376747-94390692 (-)
GRCh38
Alpha-1-Antitrypsin Deficiency
Pulmonary Disease, Chronic Obstructive; COPD
P01009 (UniProt | EBI)
NM_000295 (RefSeq)
mouse Serpina1a MGI:891971 (MGI)
20700 (Entrez Gene)
Gene Tree
VISTA-Point
Chr12 52.98 cM Chr12:103853589-103863562 (-)
GRCm38
OTTMUSG00000023942 (VEGA)
OTTMUSP00000028351 (VEGA)
OTTMUST00000058509 (VEGA)
Serpina1b MGI:891970 (MGI)
20701 (Entrez Gene)
Gene Tree
VISTA-Point
Chr12 52.98 cM Chr12:103728156-103740515 (-)
GRCm38
OTTMUSG00000035410 (VEGA)
OTTMUSP00000049718 (VEGA)
OTTMUST00000090560 (VEGA)
Serpina1c MGI:891969 (MGI)
20702 (Entrez Gene)
Gene Tree
VISTA-Point
Chr12 52.98 cM Chr12:103894926-103904887 (-)
GRCm38
OTTMUSG00000023935 (VEGA)
OTTMUSP00000028336 (VEGA)
OTTMUST00000058482 (VEGA)
Serpina1d MGI:891968 (MGI)
20703 (Entrez Gene)
Gene Tree
VISTA-Point
Chr12 52.98 cM Chr12:103763594-103773592 (-)
GRCm38
OTTMUSG00000027640 (VEGA)
OTTMUSP00000034565 (VEGA)
OTTMUST00000068385 (VEGA)
Serpina1e MGI:891967 (MGI)
20704 (Entrez Gene)
Gene Tree
VISTA-Point
Chr12 52.98 cM Chr12:103946931-103958975 (-)
GRCm38
OTTMUSG00000027635 (VEGA)
OTTMUSP00000034559 (VEGA)
OTTMUST00000068380 (VEGA)
rat Serpina1 24648 (Entrez Gene)
Chr6 q32 P17475 (UniProt | EBI)
NM_022519 (RefSeq)
chimpanzee SERPINA1 467541 (Entrez Gene)
Chr14 XP_003314546 (RefSeq)
rhesus macaque SERPINA1 701361 (Entrez Gene)
Chr7 NP_001252946 (RefSeq)
NM_001266017 (RefSeq)
cattle SERPINA1 280699 (Entrez Gene)
Chr21 P34955 (UniProt | EBI)
NM_173882 (RefSeq)
dog SERPINA1 480422 (Entrez Gene)
Chr8 NP_001073578 (RefSeq)
NM_001080109 (RefSeq)
chicken SERPINA1 423434 (Entrez Gene)
Chr5 NP_001264422 (RefSeq)
NM_001277493 (RefSeq)
SERPINA4 423433 (Entrez Gene)
Chr5 NP_001264421 (RefSeq)
NM_001277492 (RefSeq)
SERPINA5 423435 (Entrez Gene)
Chr5 XP_421344 (RefSeq)
SERPINA9 423436 (Entrez Gene)
Chr5 XP_421345 (RefSeq)
western clawed frog LOC100488834 100488834 (Entrez Gene)
ChrUN XP_002936115 (RefSeq)
serpina1 100145012 (Entrez Gene)
ChrUN XP_002936109 (RefSeq)
serpina3k 496632 (Entrez Gene)
ChrUN XP_002936116 (RefSeq)
zebrafish serpina1 322701 (Entrez Gene)
Chr20 NP_001071226 (RefSeq)
NM_001077758 (RefSeq)
serpina1l 321195 (Entrez Gene)
Chr20 NP_001013277 (RefSeq)
NM_001013259 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory