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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MMUT HGNC:7526 (HGNC)
4594 (Entrez Gene)
609058 (OMIM)
Methylmalonyl-CoA mutase (MyGene.info)
HGNC homology
Chr6 p12.3 Chr6:49430360-49463328 (-)
methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency
P22033 (UniProt | EBI)
NM_000255 (RefSeq)
mouse Mmut MGI:97239 (MGI)
17850 (Entrez Gene)
Gene Tree
HGNC homology
Chr17 19.55 cM Chr17:40934685-40961988 (+)
methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency
ENSMUSG00000023921 (Ensembl Gene Model)
ENSMUSP00000130941 (Ensembl)
ENSMUST00000169611 (Ensembl)
rat Mmut 688517 (Entrez Gene)
Chr9 q13 XP_001067239 (RefSeq)
chimpanzee MMUT 463198 (Entrez Gene)
Chr6 XP_009449696 (RefSeq)
cattle MMUT 280871 (Entrez Gene)
Chr23 Q9GK13 (UniProt | EBI)
NM_173939 (RefSeq)
dog MMUT 474930 (Entrez Gene)
Chr12 XP_022281843 (RefSeq)
chicken MUT 422049 (Entrez Gene)
Chr3 XP_004935976 (RefSeq)
zebrafish mut 569581 (Entrez Gene)
Chr20 NP_001092696 (RefSeq)
NM_001099226 (RefSeq)
frog, western clawed mmut 100379804 (Entrez Gene)
Chr5 XP_004915009 (RefSeq)
macaque, rhesus MMUT 706189 (Entrez Gene)
Chr4 NP_001248490 (RefSeq)
NM_001261561 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory