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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ITGB2 HGNC:6155 (HGNC)
3689 (Entrez Gene)
600065 (OMIM)
CD18 (MyGene.info)
HGNC homology
Chr21 q22.3 Chr21:44885949-44928873 (-)
leukocyte adhesion deficiency 1
P05107 (UniProt | EBI)
NM_000211 (RefSeq)
mouse Itgb2 MGI:96611 (MGI)
16414 (Entrez Gene)
Gene Tree
HGNC homology
Chr10 39.72 cM Chr10:77530329-77565708 (+)
leukocyte adhesion deficiency 1
16414 (NCBI Gene Model)
P11835 (UniProt | EBI)
NM_008404 (RefSeq)
rat Itgb2 309684 (Entrez Gene)
Chr20 p12 NP_001032869 (RefSeq)
NM_001037780 (RefSeq)
chimpanzee ITGB2 458607 (Entrez Gene)
Chr21 NP_001029294 (RefSeq)
NM_001034122 (RefSeq)
cattle ITGB2 281877 (Entrez Gene)
Chr1 P32592 (UniProt | EBI)
NM_175781 (RefSeq)
dog ITGB2 403770 (Entrez Gene)
Chr31 XP_022268938 (RefSeq)
chicken ITGB2 396181 (Entrez Gene)
Chr7 NP_990582 (RefSeq)
NM_205251 (RefSeq)
zebrafish itgb2 557797 (Entrez Gene)
Chr9 XP_686012 (RefSeq)
frog, western clawed itgb2 100492659 (Entrez Gene)
Chr9 XP_031749008 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory