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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human INSR HGNC:6091 (HGNC)
3643 (Entrez Gene)
147670 (OMIM)
Insulin receptor (MyGene.info)
HGNC homology
Chr19 p13.2 Chr19:7112255-7294405 (-)
Donohue syndrome
familial hyperinsulinemic hypoglycemia 5
P06213 (UniProt | EBI)
NM_001079817 (RefSeq)
mouse Insr MGI:96575 (MGI)
16337 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 1.82 cM Chr8:3150922-3279649 (-)
16337 (NCBI Gene Model)
P15208 (UniProt | EBI)
NM_001330056 (RefSeq)
rat Insr 24954 (Entrez Gene)
Chr12 p12 P15127 (UniProt | EBI)
NM_017071 (RefSeq)
chimpanzee LOC455650 455650 (Entrez Gene)
cattle INSR 408017 (Entrez Gene)
Chr7 XP_005208874 (RefSeq)
dog INSR 484990 (Entrez Gene)
Chr20 XP_005633279 (RefSeq)
chicken INSR 420133 (Entrez Gene)
Chr28 XP_001233399 (RefSeq)
zebrafish insra 245699 (Entrez Gene)
Chr2 NP_001136144 (RefSeq)
NM_001142672 (RefSeq)
insrb 245700 (Entrez Gene)
Chr22 NP_001116701 (RefSeq)
NM_001123229 (RefSeq)
frog, western clawed insr 100492718 (Entrez Gene)
Chr1 XP_002934425 (RefSeq)
macaque, rhesus INSR 706009 (Entrez Gene)
Chr19 Q28516 (UniProt | EBI)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory