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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
20090

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human INSR HGNC:6091 (HGNC)
3643 (Entrez Gene)
147670 (OMIM)
Chr19 p13.3-p13.2 Chr19:7112255-7294328 (-)
GRCh38
Diabetes Mellitus, Insulin-Resistant, with Acanthosis Nigricans
Donohue Syndrome
Hyperinsulinemic Hypoglycemia, Familial, 5; HHF5
Pineal Hyperplasia, Insulin-Resistant Diabetes Mellitus, and Somatic Abnormalities
P06213 (UniProt | EBI)
NM_000208 (RefSeq)
mouse Insr MGI:96575 (MGI)
16337 (Entrez Gene)
Gene Tree
VISTA-Point
Chr8 1.82 cM Chr8:3150922-3279617 (-)
GRCm38
Polycystic Ovary Syndrome 1; PCOS1
OTTMUSG00000031438 (VEGA)
OTTMUSP00000041297 (VEGA)
OTTMUST00000077897 (VEGA)
rat Insr 24954 (Entrez Gene)
Chr12 q12 P15127 (UniProt | EBI)
NM_017071 (RefSeq)
chimpanzee INSR 455650 (Entrez Gene)
Chr19 XP_512324 (RefSeq)
rhesus macaque INSR 706009 (Entrez Gene)
Chr19 XP_001094337 (RefSeq)
cattle INSR 408017 (Entrez Gene)
Chr7 XP_590552 (RefSeq)
dog INSR 484990 (Entrez Gene)
Chr20 XP_005633279 (RefSeq)
chicken INSR 420133 (Entrez Gene)
Chr28 XP_001233399 (RefSeq)
zebrafish insra 245699 (Entrez Gene)
Chr2 NP_001136144 (RefSeq)
NM_001142672 (RefSeq)
insrb 245700 (Entrez Gene)
Chr22 NP_001116701 (RefSeq)
NM_001123229 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory