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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human HSD11B2 HGNC:5209 (HGNC)
3291 (Entrez Gene)
614232 (OMIM)
HGNC homology
Chr16 q22 Chr16:67431133-67437553 (+)
Apparent Mineralocorticoid Excess; AME
P80365 (UniProt | EBI)
NM_000196 (RefSeq)
mouse Hsd11b2 MGI:104720 (MGI)
15484 (Entrez Gene)
Gene Tree
Chr8 53.04 cM Chr8:105518746-105523984 (+)
Apparent Mineralocorticoid Excess; AME
ENSMUSG00000031891 (Ensembl Gene Model)
ENSMUSP00000034363 (Ensembl)
ENSMUST00000034363 (Ensembl)
rat Hsd11b2 25117 (Entrez Gene)
Chr19 q11-q12 P50233 (UniProt | EBI)
NM_017081 (RefSeq)
chimpanzee HSD11B2 468001 (Entrez Gene)
Chr16 XP_523393 (RefSeq)
rhesus macaque HSD11B2 574396 (Entrez Gene)
Chr20 XP_014981886 (RefSeq)
cattle HSD11B2 282434 (Entrez Gene)
Chr18 O77667 (UniProt | EBI)
NM_174642 (RefSeq)
dog HSD11B2 489758 (Entrez Gene)
Chr5 XP_005620879 (RefSeq)
chicken HSD11B2 100857283 (Entrez Gene)
HSD11B2L 100858361 (Entrez Gene)
Chr11 XP_015134686 (RefSeq)
western clawed frog hsd11b2 100489854 (Entrez Gene)
ChrUN XP_002937366 (RefSeq)
zebrafish hsd11b2 334098 (Entrez Gene)
Chr7 NP_997885 (RefSeq)
NM_212720 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory