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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CFH HGNC:4883 (HGNC)
3075 (Entrez Gene)
134370 (OMIM)
HGNC homology
Chr1 q32 Chr1:196651878-196747504 (+)
Basal Laminar Drusen
Complement Factor H Deficiency; CFHD
Hemolytic Uremic Syndrome, Atypical, Susceptibility to, 1; AHUS1
Macular Degeneration, Age-Related, 4; ARMD4
P08603 (UniProt | EBI)
NM_001014975 (RefSeq)
mouse Cfh MGI:88385 (MGI)
12628 (Entrez Gene)
Gene Tree
Chr1 61.62 cM Chr1:140084708-140183764 (-)
Hemolytic Uremic Syndrome, Atypical, Susceptibility to, 1; AHUS1
Macular Degeneration, Age-Related, 4; ARMD4
OTTMUSG00000024648 (VEGA)
OTTMUSP00000029568 (VEGA)
OTTMUST00000060596 (VEGA)
rat Cfh 155012 (Entrez Gene)
Chr13 q13 NP_569093 (RefSeq)
NM_130409 (RefSeq)
chimpanzee CFH 457601 (Entrez Gene)
Chr1 XP_001136531 (RefSeq)
rhesus macaque CFH 717346 (Entrez Gene)
Chr1 XP_014976356 (RefSeq)
cattle CFH 280816 (Entrez Gene)
Chr16 Q28085 (UniProt | EBI)
NM_001033936 (RefSeq)
dog CFH 478952 (Entrez Gene)
Chr38 XP_536110 (RefSeq)
chicken RP4-608O15.3 429057 (Entrez Gene)
Chr8 XP_426613 (RefSeq)
western clawed frog cfh 394826 (Entrez Gene)
ChrUN NP_989218 (RefSeq)
NM_203887 (RefSeq)
f13b 100379841 (Entrez Gene)
ChrUN XP_002938378 (RefSeq)
LOC100487763 100487763 (Entrez Gene)
ChrUN XP_012817932 (RefSeq)
LOC100491927 100491927 (Entrez Gene)
LOC100492100 100492100 (Entrez Gene)
ChrUN XP_002932215 (RefSeq)
LOC100496324 100496324 (Entrez Gene)
ChrUN XP_002938373 (RefSeq)
LOC100497496 100497496 (Entrez Gene)
ChrUN XP_002938379 (RefSeq)
LOC100497803 100497803 (Entrez Gene)
ChrUN XP_002938381 (RefSeq)
LOC100497957 100497957 (Entrez Gene)
ChrUN XP_004919521 (RefSeq)
LOC101731666 101731666 (Entrez Gene)
ChrUN XP_004921059 (RefSeq)
zebrafish cfh 553297 (Entrez Gene)
Chr22 NP_001186119 (RefSeq)
NM_001199190 (RefSeq)
cfhl1 570905 (Entrez Gene)
Chr22 NP_001032792 (RefSeq)
NM_001037703 (RefSeq)
cfhl2 492777 (Entrez Gene)
Chr22 NP_001007419 (RefSeq)
NM_001007418 (RefSeq)
cfhl3 100526816 (Entrez Gene)
Chr22 NP_001186120 (RefSeq)
NM_001199191 (RefSeq)
LOC100535929 100535929 (Entrez Gene)
LOC100536017 100536017 (Entrez Gene)
LOC100536554 100536554 (Entrez Gene)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory