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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LPL HGNC:6677 (HGNC)
4023 (Entrez Gene)
609708 (OMIM)
Lipoprotein lipase (MyGene.info)
HGNC homology
Chr8 p21.3 Chr8:19939071-19967259 (+)
familial combined hyperlipidemia
familial lipoprotein lipase deficiency
P06858 (UniProt | EBI)
NM_000237 (RefSeq)
mouse Lpl MGI:96820 (MGI)
16956 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 33.88 cM Chr8:68880491-68907448 (+)
familial lipoprotein lipase deficiency
OTTMUSG00000036084 (VEGA)
OTTMUSP00000051333 (VEGA)
OTTMUST00000092755 (VEGA)
rat Lpl 24539 (Entrez Gene)
Chr16 p14 Q06000 (UniProt | EBI)
NM_012598 (RefSeq)
chimpanzee LPL 464031 (Entrez Gene)
Chr8 XP_016814670 (RefSeq)
cattle LPL 280843 (Entrez Gene)
Chr8 P11151 (UniProt | EBI)
NM_001075120 (RefSeq)
dog LPL 403626 (Entrez Gene)
Chr25 XP_005635791 (RefSeq)
chicken LPL 396219 (Entrez Gene)
ChrZ P11602 (UniProt | EBI)
NM_205282 (RefSeq)
zebrafish LOC101884800 101884800 (Entrez Gene)
Chr2 XP_005174466 (RefSeq)
lpl 30354 (Entrez Gene)
Chr22 NP_571202 (RefSeq)
NM_131127 (RefSeq)
frog, western clawed lpl 100127862 (Entrez Gene)
Chr1 XP_002934038 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory