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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PHB HGNC:8912 (HGNC)
5245 (Entrez Gene)
176705 (OMIM)
Prohibitin (MyGene.info)
HGNC homology
Chr17 q21.33 Chr17:49404048-49414905 (-)
breast cancer
P35232 (UniProt | EBI)
NM_001281497 (RefSeq)
mouse Phb MGI:97572 (MGI)
18673 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 59.01 cM Chr11:95666957-95680773 (+)
OTTMUSG00000001749 (VEGA)
OTTMUSP00000001681 (VEGA)
OTTMUST00000003483 (VEGA)
rat Phb 25344 (Entrez Gene)
Chr10 P67779 (UniProt | EBI)
NM_031851 (RefSeq)
chimpanzee PHB 455205 (Entrez Gene)
Chr17 NP_001233332 (RefSeq)
NM_001246403 (RefSeq)
cattle PHB 530409 (Entrez Gene)
Chr19 Q3T165 (UniProt | EBI)
NM_001034572 (RefSeq)
dog PHB 480547 (Entrez Gene)
Chr9 NP_001103649 (RefSeq)
NM_001110179 (RefSeq)
chicken PHB 419980 (Entrez Gene)
Chr27 P84173 (UniProt | EBI)
NM_001177735 (RefSeq)
zebrafish phb 321346 (Entrez Gene)
Chr3 NP_958454 (RefSeq)
NM_201297 (RefSeq)
frog, western clawed phb 394635 (Entrez Gene)
Chr10 NP_989038 (RefSeq)
NM_203707 (RefSeq)
macaque, rhesus PHB 699334 (Entrez Gene)
Chr16 NP_001253252 (RefSeq)
NM_001266323 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory