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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human IQSEC2 HGNC:29059 (HGNC)
23096 (Entrez Gene)
300522 (OMIM)
HGNC homology
ChrX p11.22 ChrX:53227454-53321350 (-)
Mental Retardation, X-Linked 1; MRX1
Q5JU85 (UniProt | EBI)
NM_001111125 (RefSeq)
mouse Iqsec2 MGI:3528396 (MGI)
245666 (Entrez Gene)
Gene Tree
ChrX 68.46 cM ChrX:152144272-152225236 (+)
OTTMUSG00000019682 (VEGA)
OTTMUSP00000021283 (VEGA)
OTTMUST00000047113 (VEGA)
rat Iqsec2 685244 (Entrez Gene)
ChrX q21 NP_001264315 (RefSeq)
NM_001277386 (RefSeq)
cattle IQSEC2 517311 (Entrez Gene)
ChrX XP_010820316 (RefSeq)
dog IQSEC2 491895 (Entrez Gene)
ChrX XP_005641431 (RefSeq)
western clawed frog iqsec2 100485600 (Entrez Gene)
ChrUN XP_004916806 (RefSeq)
zebrafish iqsec2 797187 (Entrez Gene)
Chr8 XP_009302417 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory