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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human P2RX7 HGNC:8537 (HGNC)
5027 (Entrez Gene)
602566 (OMIM)
HGNC homology
Chr12 q24 Chr12:121132819-121186551 (+)
Q99572 (UniProt | EBI)
NM_177427 (RefSeq)
mouse P2rx7 MGI:1339957 (MGI)
18439 (Entrez Gene)
Gene Tree
Chr5 62.5 cM Chr5:122643911-122691432 (+)
OTTMUSG00000026740 (VEGA)
OTTMUSP00000033090 (VEGA)
OTTMUST00000066137 (VEGA)
chimpanzee P2RX7 452318 (Entrez Gene)
Chr12 XP_509436 (RefSeq)
rhesus macaque P2RX7 699455 (Entrez Gene)
Chr11 XP_001092531 (RefSeq)
cattle P2RX7 286814 (Entrez Gene)
Chr17 NP_001193445 (RefSeq)
NM_001206516 (RefSeq)
dog P2RX7 448778 (Entrez Gene)
Chr26 NP_001106927 (RefSeq)
NM_001113456 (RefSeq)
chicken P2RX7 771952 (Entrez Gene)
Chr15 XP_001235163 (RefSeq)
western clawed frog LOC100490662 100490662 (Entrez Gene)
ChrUN XP_012811320 (RefSeq)
p2rx7 100490828 (Entrez Gene)
ChrUN XP_012824363 (RefSeq)
zebrafish p2rx7 387298 (Entrez Gene)
Chr8 NP_945335 (RefSeq)
NM_198984 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.01
The Jackson Laboratory