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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human GPNMB HGNC:4462 (HGNC)
10457 (Entrez Gene)
604368 (OMIM)
GPNMB (MyGene.info)
HGNC homology
Chr7 p15.3 Chr7:23246206-23275110 (+)
Q14956 (UniProt | EBI)
NM_002510 (RefSeq)
mouse Gpnmb MGI:1934765 (MGI)
93695 (Entrez Gene)
Gene Tree
HGNC homology
Chr6 23.82 cM Chr6:49036546-49070929 (+)
pigment dispersion syndrome
OTTMUSG00000057401 (VEGA)
OTTMUSP00000073829 (VEGA)
OTTMUST00000141205 (VEGA)
rat Gpnmb 113955 (Entrez Gene)
Chr4 q24 Q6P7C7 (UniProt | EBI)
NM_133298 (RefSeq)
chimpanzee GPNMB 463289 (Entrez Gene)
Chr7 XP_001157101 (RefSeq)
cattle GPNMB 509600 (Entrez Gene)
Chr4 NP_001033154 (RefSeq)
NM_001038065 (RefSeq)
dog GPNMB 482355 (Entrez Gene)
Chr14 XP_539472 (RefSeq)
chicken GPNMB 428431 (Entrez Gene)
Chr2 XP_425991 (RefSeq)
zebrafish gpnmb 563348 (Entrez Gene)
Chr19 XP_691804 (RefSeq)
frog, western clawed gpnmb 100124325 (Entrez Gene)
Chr6 NP_001124514 (RefSeq)
NM_001131042 (RefSeq)
macaque, rhesus GPNMB 704990 (Entrez Gene)
Chr3 NP_001253579 (RefSeq)
NM_001266650 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory