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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human NFIX HGNC:7788 (HGNC)
4784 (Entrez Gene)
164005 (OMIM)
HGNC homology
Chr19 p13.3 Chr19:12995756-13098796 (+)
Marshall-Smith Syndrome; MRSHSS
Sotos Syndrome 2; SOTOS2
Q14938 (UniProt | EBI)
NM_001271043 (RefSeq)
mouse Nfix MGI:97311 (MGI)
18032 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 41.02 cM Chr8:84699876-84800344 (-)
Osteochondrodysplasia, Rhizomelic, with Callosal Agenesis, Thrombocytopenia, Hydrocephalus, and Hypertension
Scheuermann Disease
OTTMUSG00000022188 (VEGA)
OTTMUSP00000025025 (VEGA)
OTTMUST00000052707 (VEGA)
rat Nf1x 81524 (Entrez Gene)
Chr19 q11 NP_110493 (RefSeq)
NM_030866 (RefSeq)
chimpanzee NFIX 468742 (Entrez Gene)
Chr19 XP_009433113 (RefSeq)
rhesus macaque NFIX 717108 (Entrez Gene)
Chr19 XP_014978541 (RefSeq)
cattle NFIX 536348 (Entrez Gene)
Chr7 XP_015319529 (RefSeq)
dog NFIX 484920 (Entrez Gene)
Chr20 XP_005632871 (RefSeq)
chicken NFIX 396207 (Entrez Gene)
Chr30 Q90932 (UniProt | EBI)
NM_205270 (RefSeq)
western clawed frog nfix 100158549 (Entrez Gene)
ChrUN NP_001121455 (RefSeq)
NM_001127983 (RefSeq)
zebrafish nfixa 555669 (Entrez Gene)
Chr1 XP_009292756 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory