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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human KIT HGNC:6342 (HGNC)
3815 (Entrez Gene)
164920 (OMIM)
CD117 (MyGene.info)
HGNC homology
Chr4 q12 Chr4:54657928-54740715 (+)
gastrointestinal stromal tumor
P10721 (UniProt | EBI)
NM_000222 (RefSeq)
mouse Kit MGI:96677 (MGI)
16590 (Entrez Gene)
Gene Tree
HGNC homology
Chr5 39.55 cM Chr5:75574916-75656722 (+)
gastrointestinal stromal tumor
macrocytic anemia
OTTMUSG00000016671 (VEGA)
OTTMUSP00000018030 (VEGA)
OTTMUST00000040351 (VEGA)
rat Kit 64030 (Entrez Gene)
Chr14 p11 NP_071600 (RefSeq)
NM_022264 (RefSeq)
chimpanzee KIT 461316 (Entrez Gene)
Chr4 XP_009446158 (RefSeq)
cattle KIT 280832 (Entrez Gene)
Chr6 P43481 (UniProt | EBI)
NM_001166484 (RefSeq)
dog KIT 403811 (Entrez Gene)
Chr13 O97799 (UniProt | EBI)
NM_001003181 (RefSeq)
chicken KIT 378783 (Entrez Gene)
Chr4 Q08156 (UniProt | EBI)
NM_204361 (RefSeq)
zebrafish kita 30256 (Entrez Gene)
Chr20 Q8JFR5 (UniProt | EBI)
NM_131053 (RefSeq)
kitb 497629 (Entrez Gene)
Chr1 NP_001137390 (RefSeq)
NM_001143918 (RefSeq)
frog, western clawed kit 100216090 (Entrez Gene)
Chr1 NP_001135545 (RefSeq)
NM_001142073 (RefSeq)
macaque, rhesus KIT 696759 (Entrez Gene)
Chr5 NP_001253024 (RefSeq)
NM_001266095 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory