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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 67, Dec 12, 2012)
187

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human KIT HGNC:6342 (HGNC)
3815 (Entrez Gene)
164920 (OMIM)
Chr4 q12 Chr4:54657928-54740715 (+)
GRCh38
Gastrointestinal Stromal Tumor; GIST
Mast Cell Disease
Piebald Trait; PBT
P10721 (UniProt | EBI)
NM_000222 (RefSeq)
mouse Kit MGI:96677 (MGI)
16590 (Entrez Gene)
Gene Tree
VISTA-Point
Chr5 39.55 cM Chr5:75574916-75656722 (+)
GRCm38
Gastrointestinal Stromal Tumor; GIST
Piebald Trait; PBT
OTTMUSG00000016671 (VEGA)
OTTMUSP00000018029 (VEGA)
OTTMUST00000040350 (VEGA)
rat Kit 64030 (Entrez Gene)
Chr14 p11 NP_071600 (RefSeq)
NM_022264 (RefSeq)
chimpanzee KIT 461316 (Entrez Gene)
Chr4 XP_517285 (RefSeq)
rhesus macaque KIT 696759 (Entrez Gene)
Chr5 NP_001253024 (RefSeq)
NM_001266095 (RefSeq)
dog KIT 403811 (Entrez Gene)
Chr13 O97799 (UniProt | EBI)
NM_001003181 (RefSeq)
chicken KIT 378783 (Entrez Gene)
Chr4 Q08156 (UniProt | EBI)
NM_204361 (RefSeq)
zebrafish kita 30256 (Entrez Gene)
Chr20 Q8JFR5 (UniProt | EBI)
NM_131053 (RefSeq)
kitb 497629 (Entrez Gene)
Chr1 NP_001137390 (RefSeq)
NM_001143918 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory