About   Help   FAQ
Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
select all deselect all Go
human LRRC8A HGNC:19027 (HGNC)
56262 (Entrez Gene)
608360 (OMIM)
Chr9 q34.11 Chr9:128882112-128918039 (+)
Agammaglobulinemia 5, Autosomal Dominant; AGM5
Q8IWT6 (UniProt | EBI)
NM_019594 (RefSeq)
mouse Lrrc8a MGI:2652847 (MGI)
241296 (Entrez Gene)
Gene Tree
Chr2 21.41 cM Chr2:30237715-30263790 (+)
OTTMUSG00000016752 (VEGA)
OTTMUSP00000018164 (VEGA)
OTTMUST00000040641 (VEGA)
rat Lrrc8a 311846 (Entrez Gene)
Chr3 p12 Q4V8I7 (UniProt | EBI)
NM_001024782 (RefSeq)
chimpanzee LRRC8A 464779 (Entrez Gene)
Chr9 XP_001161421 (RefSeq)
rhesus macaque LRRC8A 717074 (Entrez Gene)
Chr15 NP_001244505 (RefSeq)
NM_001257576 (RefSeq)
cattle LRRC8A 505605 (Entrez Gene)
Chr11 NP_001070275 (RefSeq)
NM_001076807 (RefSeq)
dog LRRC8A 491309 (Entrez Gene)
Chr9 XP_548430 (RefSeq)
chicken LOC100858917 100858917 (Entrez Gene)
Chr17 XP_003642331 (RefSeq)
LRRC8A 417201 (Entrez Gene)
Chr17 XP_415484 (RefSeq)
western clawed frog lrrc8a 100492279 (Entrez Gene)
ChrUN XP_002935552 (RefSeq)
zebrafish lrrc8a 327642 (Entrez Gene)
Chr21 NP_001025120 (RefSeq)
NM_001029949 (RefSeq)
si:ch211-236k19.7 557928 (Entrez Gene)
Chr5 XP_686175 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 5.21
The Jackson Laboratory