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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LRRC8A HGNC:19027 (HGNC)
56262 (Entrez Gene)
608360 (OMIM)
LRRC8A (MyGene.info)
HGNC homology
Chr9 q34.11 Chr9:128882112-128918042 (+)
Q8IWT6 (UniProt | EBI)
NM_019594 (RefSeq)
mouse Lrrc8a MGI:2652847 (MGI)
241296 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 21.41 cM Chr2:30237715-30263790 (+)
OTTMUSG00000016752 (VEGA)
OTTMUSP00000018165 (VEGA)
OTTMUST00000040642 (VEGA)
rat Lrrc8a 311846 (Entrez Gene)
Chr3 p12 Q4V8I7 (UniProt | EBI)
NM_001024782 (RefSeq)
chimpanzee LRRC8A 464779 (Entrez Gene)
Chr9 XP_001161463 (RefSeq)
cattle LRRC8A 505605 (Entrez Gene)
Chr11 NP_001070275 (RefSeq)
NM_001076807 (RefSeq)
dog LRRC8A 491309 (Entrez Gene)
Chr9 XP_005625320 (RefSeq)
chicken LOC100858917 100858917 (Entrez Gene)
LRRC8A 417201 (Entrez Gene)
Chr17 XP_003642331 (RefSeq)
zebrafish lrrc8aa 327642 (Entrez Gene)
Chr21 NP_001025120 (RefSeq)
NM_001029949 (RefSeq)
lrrc8ab 557928 (Entrez Gene)
Chr5 XP_686175 (RefSeq)
frog, western clawed lrrc8a 100492279 (Entrez Gene)
Chr8 XP_002935552 (RefSeq)
macaque, rhesus LRRC8A 717074 (Entrez Gene)
Chr15 NP_001244505 (RefSeq)
NM_001257576 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory