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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human NBN HGNC:7652 (HGNC)
4683 (Entrez Gene)
602667 (OMIM)
Nibrin (MyGene.info)
HGNC homology
Chr8 q21.3 Chr8:89933336-89984733 (-)
acute lymphocytic leukemia
aplastic anemia
Nijmegen breakage syndrome
O60934 (UniProt | EBI)
NM_002485 (RefSeq)
mouse Nbn MGI:1351625 (MGI)
27354 (Entrez Gene)
Gene Tree
HGNC homology
Chr4 6.66 cM Chr4:15957925-15992589 (+)
Nijmegen breakage syndrome
ENSMUSG00000028224 (Ensembl Gene Model)
ENSMUSP00000029879 (Ensembl)
ENSMUST00000029879 (Ensembl)
rat Nbn 85482 (Entrez Gene)
Chr5 q13 Q9JIL9 (UniProt | EBI)
NM_138873 (RefSeq)
chimpanzee NBN 464278 (Entrez Gene)
Chr8 XP_016815146 (RefSeq)
cattle NBN 522943 (Entrez Gene)
Chr14 NP_001069305 (RefSeq)
NM_001075837 (RefSeq)
dog NBN 611315 (Entrez Gene)
Chr29 XP_013964755 (RefSeq)
chicken NBN 374246 (Entrez Gene)
Chr2 Q9DE07 (UniProt | EBI)
NM_204337 (RefSeq)
zebrafish nbn 544655 (Entrez Gene)
Chr16 Q5I2W8 (UniProt | EBI)
NM_001014819 (RefSeq)
frog, western clawed nbn 733826 (Entrez Gene)
Chr6 XP_017950647 (RefSeq)
macaque, rhesus NBN 695912 (Entrez Gene)
Chr8 NP_001252668 (RefSeq)
NM_001265739 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory