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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MSX1 HGNC:7391 (HGNC)
4487 (Entrez Gene)
142983 (OMIM)
MSX1 (MyGene.info)
HGNC homology
Chr4 p16.2 Chr4:4859665-4863936 (+)
orofacial cleft
tooth agenesis
tooth and nail syndrome
P28360 (UniProt | EBI)
NM_002448 (RefSeq)
mouse Msx1 MGI:97168 (MGI)
17701 (Entrez Gene)
Gene Tree
HGNC homology
Chr5 20.21 cM Chr5:37820485-37824583 (-)
orofacial cleft
tooth agenesis
OTTMUSG00000021309 (VEGA)
OTTMUSP00000023597 (VEGA)
OTTMUST00000050525 (VEGA)
rat Msx1 81710 (Entrez Gene)
Chr14 q21 NP_112321 (RefSeq)
NM_031059 (RefSeq)
chimpanzee MSX1 461092 (Entrez Gene)
Chr4 Q2VL88 (UniProt | EBI)
NM_001195262 (RefSeq)
cattle MSX1 286872 (Entrez Gene)
Chr6 O02786 (UniProt | EBI)
NM_174798 (RefSeq)
dog MSX1 488828 (Entrez Gene)
Chr3 XP_545946 (RefSeq)
chicken MSX1 396484 (Entrez Gene)
Chr4 P28361 (UniProt | EBI)
NM_205488 (RefSeq)
zebrafish msx1a 30527 (Entrez Gene)
Chr14 NP_571348 (RefSeq)
NM_001033589 (RefSeq)
frog, western clawed msx1 394692 (Entrez Gene)
Chr1 NP_001032329 (RefSeq)
NM_001037252 (RefSeq)
macaque, rhesus MSX1 722771 (Entrez Gene)
Chr5 Q2VL87 (UniProt | EBI)
NM_001040416 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory