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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
181

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human JAK3 HGNC:6193 (HGNC)
3718 (Entrez Gene)
600173 (OMIM)
Chr19 p13.1 Chr19:17824782-17848071 (-)
GRCh38
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Positive, Nk Cell-Negative
P52333 (UniProt | EBI)
NM_000215 (RefSeq)
mouse Jak3 MGI:99928 (MGI)
16453 (Entrez Gene)
Gene Tree
VISTA-Point
Chr8 34.43 cM Chr8:71676296-71690575 (+)
GRCm38
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Positive, Nk Cell-Positive
OTTMUSG00000021111 (VEGA)
OTTMUSP00000023248 (VEGA)
OTTMUST00000049963 (VEGA)
rat Jak3 25326 (Entrez Gene)
Chr16 p14 Q63272 (UniProt | EBI)
NM_012855 (RefSeq)
chimpanzee JAK3 455848 (Entrez Gene)
Chr19 XP_512502 (RefSeq)
rhesus macaque LOC720040 720040 (Entrez Gene)
Chr19 XP_001115037 (RefSeq)
cattle JAK3 538276 (Entrez Gene)
Chr7 XP_002688585 (RefSeq)
dog JAK3 610004 (Entrez Gene)
Chr20 XP_005632774 (RefSeq)
chicken JAK3 395845 (Entrez Gene)
ChrUN NP_990327 (RefSeq)
NM_204996 (RefSeq)
western clawed frog jak3 100135373 (Entrez Gene)
ChrUN NP_001107517 (RefSeq)
NM_001114045 (RefSeq)
zebrafish jak3 561370 (Entrez Gene)
Chr8 XP_002663133 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory