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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human JAK3 HGNC:6193 (HGNC)
3718 (Entrez Gene)
600173 (OMIM)
Janus kinase 3 (MyGene.info)
HGNC homology
Chr19 p13.11 Chr19:17824782-17848071 (-)
janus kinase-3 deficiency
P52333 (UniProt | EBI)
NM_000215 (RefSeq)
mouse Jak3 MGI:99928 (MGI)
16453 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 34.43 cM Chr8:71676296-71690575 (+)
severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive
OTTMUSG00000021111 (VEGA)
OTTMUSP00000023247 (VEGA)
OTTMUST00000049960 (VEGA)
rat Jak3 25326 (Entrez Gene)
Chr16 p14 Q63272 (UniProt | EBI)
NM_012855 (RefSeq)
chimpanzee JAK3 455848 (Entrez Gene)
cattle JAK3 538276 (Entrez Gene)
Chr7 XP_015327405 (RefSeq)
dog JAK3 610004 (Entrez Gene)
Chr20 XP_013977869 (RefSeq)
chicken JAK3 395845 (Entrez Gene)
Chr28 NP_990327 (RefSeq)
NM_204996 (RefSeq)
zebrafish jak3 561370 (Entrez Gene)
Chr8 XP_002663133 (RefSeq)
frog, western clawed jak3 100135373 (Entrez Gene)
Chr1 NP_001107517 (RefSeq)
NM_001114045 (RefSeq)
macaque, rhesus JAK3 720040 (Entrez Gene)
Chr19 XP_014978766 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory