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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MEST HGNC:7028 (HGNC)
4232 (Entrez Gene)
601029 (OMIM)
HGNC homology
Chr7 q32 Chr7:130486175-130506297 (+)
Q5EB52 (UniProt | EBI)
NM_002402 (RefSeq)
mouse Mest MGI:96968 (MGI)
17294 (Entrez Gene)
Gene Tree
HGNC homology
Chr6 12.53 cM Chr6:30723547-30748465 (+)
Barth Syndrome; BTHS
OTTMUSG00000014405 (VEGA)
OTTMUSP00000015297 (VEGA)
OTTMUST00000034122 (VEGA)
rat Mest 58827 (Entrez Gene)
Chr4 q44 Q6P5P5 (UniProt | EBI)
NM_001009617 (RefSeq)
chimpanzee MEST 463729 (Entrez Gene)
Chr7 XP_009452486 (RefSeq)
rhesus macaque MEST 703327 (Entrez Gene)
Chr3 NP_001247871 (RefSeq)
NM_001260942 (RefSeq)
cattle MEST 404180 (Entrez Gene)
Chr4 Q2HJM9 (UniProt | EBI)
NM_001083368 (RefSeq)
dog MEST 607717 (Entrez Gene)
Chr14 XP_005628427 (RefSeq)
chicken MEST 427684 (Entrez Gene)
Chr1 XP_015142710 (RefSeq)
western clawed frog mest 448261 (Entrez Gene)
ChrUN NP_001005789 (RefSeq)
NM_001005789 (RefSeq)
zebrafish mest 30242 (Entrez Gene)
Chr4 NP_571118 (RefSeq)
NM_131043 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory