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Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MEST HGNC:7028 (HGNC)
4232 (Entrez Gene)
601029 (OMIM)
Chr7 q32 Chr7:130486175-130506297 (+)
Q5EB52 (UniProt | EBI)
NM_002402 (RefSeq)
mouse Mest MGI:96968 (MGI)
17294 (Entrez Gene)
Gene Tree
Chr6 12.53 cM Chr6:30723547-30744394 (+)
Barth Syndrome; BTHS
OTTMUSG00000014405 (VEGA)
OTTMUSP00000015297 (VEGA)
OTTMUST00000034122 (VEGA)
rat Mest 58827 (Entrez Gene)
Chr4 q44 Q6P5P5 (UniProt | EBI)
NM_001009617 (RefSeq)
chimpanzee MEST 463729 (Entrez Gene)
Chr7 XP_519382 (RefSeq)
rhesus macaque MEST 703327 (Entrez Gene)
Chr3 NP_001247871 (RefSeq)
NM_001260942 (RefSeq)
cattle MEST 404180 (Entrez Gene)
Chr4 Q2HJM9 (UniProt | EBI)
NM_001083368 (RefSeq)
dog MEST 607717 (Entrez Gene)
Chr14 XP_848679 (RefSeq)
chicken MEST 427684 (Entrez Gene)
Chr1 XP_425258 (RefSeq)
western clawed frog mest 448261 (Entrez Gene)
ChrUN NP_001005789 (RefSeq)
NM_001005789 (RefSeq)
zebrafish mest 30242 (Entrez Gene)
Chr4 NP_571118 (RefSeq)
NM_131043 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory