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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LRP4 HGNC:6696 (HGNC)
4038 (Entrez Gene)
604270 (OMIM)
HGNC homology
Chr11 p11.2 Chr11:46856717-46918622 (-)
Cenani-Lenz Syndactyly Syndrome; CLSS
Myasthenic Syndrome, Congenital, 17; CMS17
Sclerosteosis 2; SOST2
O75096 (UniProt | EBI)
NM_002334 (RefSeq)
mouse Lrp4 MGI:2442252 (MGI)
228357 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 50.63 cM Chr2:91457511-91513779 (+)
Cenani-Lenz Syndactyly Syndrome; CLSS
OTTMUSG00000014247 (VEGA)
OTTMUSP00000015050 (VEGA)
OTTMUST00000033533 (VEGA)
rat Lrp4 83469 (Entrez Gene)
Chr3 q24 Q9QYP1 (UniProt | EBI)
NM_031322 (RefSeq)
chimpanzee LRP4 451161 (Entrez Gene)
Chr11 XP_009458674 (RefSeq)
rhesus macaque LRP4 714038 (Entrez Gene)
Chr14 XP_001111133 (RefSeq)
cattle LRP4 504317 (Entrez Gene)
Chr15 NP_001071311 (RefSeq)
NM_001077843 (RefSeq)
dog LRP4 483628 (Entrez Gene)
Chr18 XP_005631328 (RefSeq)
chicken LRP4 423189 (Entrez Gene)
Chr5 XP_421114 (RefSeq)
western clawed frog lrp4 100101694 (Entrez Gene)
ChrUN XP_012809498 (RefSeq)
zebrafish lrp4 100331602 (Entrez Gene)
Chr7 XP_009301924 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.0
The Jackson Laboratory