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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LRP4 HGNC:6696 (HGNC)
4038 (Entrez Gene)
604270 (OMIM)
HGNC homology
Chr11 p11.2 Chr11:46854715-46918622 (-)
Cenani-Lenz syndactyly syndrome
congenital myasthenic syndrome 17
sclerosteosis 2
O75096 (UniProt | EBI)
NM_002334 (RefSeq)
mouse Lrp4 MGI:2442252 (MGI)
228357 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 50.63 cM Chr2:91457511-91513779 (+)
sclerosteosis 2
ENSMUSG00000027253 (Ensembl Gene Model)
ENSMUSP00000028689 (Ensembl)
ENSMUST00000028689 (Ensembl)
rat Lrp4 83469 (Entrez Gene)
Chr3 q24 Q9QYP1 (UniProt | EBI)
NM_031322 (RefSeq)
chimpanzee LRP4 451161 (Entrez Gene)
Chr11 XP_009458674 (RefSeq)
cattle LRP4 504317 (Entrez Gene)
Chr15 NP_001071311 (RefSeq)
NM_001077843 (RefSeq)
dog LRP4 483628 (Entrez Gene)
Chr18 XP_022261184 (RefSeq)
chicken LRP4 423189 (Entrez Gene)
Chr5 XP_004941641 (RefSeq)
zebrafish lrp4 100331602 (Entrez Gene)
frog, western clawed lrp4 100101694 (Entrez Gene)
Chr4 XP_031756584 (RefSeq)
macaque, rhesus LRP4 714038 (Entrez Gene)
Chr14 XP_014969841 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory