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Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ITGB4 HGNC:6158 (HGNC)
3691 (Entrez Gene)
147557 (OMIM)
Chr17 q25 Chr17:75721436-75757818 (+)
Epidermolysis Bullosa Junctionalis with Pyloric Atresia
Epidermolysis Bullosa Simplex, Localized
Epidermolysis Bullosa, Junctional, Non-Herlitz Type
P16144 (UniProt | EBI)
NM_000213 (RefSeq)
mouse Itgb4 MGI:96613 (MGI)
192897 (Entrez Gene)
Gene Tree
Chr11 80.91 cM Chr11:115974709-116008412 (+)
Epidermolysis Bullosa Junctionalis with Pyloric Atresia
Epidermolysis Bullosa, Junctional, Non-Herlitz Type
OTTMUSG00000003650 (VEGA)
OTTMUSP00000003828 (VEGA)
OTTMUST00000007886 (VEGA)
rat Itgb4 25724 (Entrez Gene)
Chr10 q32.3 Q64632 (UniProt | EBI)
NM_013180 (RefSeq)
chimpanzee ITGB4 454887 (Entrez Gene)
Chr17 XP_003315785 (RefSeq)
rhesus macaque ITGB4 703770 (Entrez Gene)
Chr16 XP_002800666 (RefSeq)
cattle ITGB4 506995 (Entrez Gene)
Chr19 NP_001180186 (RefSeq)
NM_001193257 (RefSeq)
dog ITGB4 483318 (Entrez Gene)
Chr9 XP_005624218 (RefSeq)
chicken ITGB4 417374 (Entrez Gene)
Chr18 XP_003642374 (RefSeq)
western clawed frog itgb4 100485847 (Entrez Gene)
ChrUN XP_002940020 (RefSeq)
zebrafish itgb4 335269 (Entrez Gene)
Chr8 NP_001019557 (RefSeq)
NM_001024386 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.20
The Jackson Laboratory