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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
17790

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PCSK9 HGNC:20001 (HGNC)
255738 (Entrez Gene)
607786 (OMIM)
Chr1 p32.3 Chr1:55039476-55064853 (+)
GRCh38
Hypercholesterolemia, Autosomal Dominant, 3; HCHOLA3
Q8NBP7 (UniProt | EBI)
NM_174936 (RefSeq)
mouse Pcsk9 MGI:2140260 (MGI)
100102 (Entrez Gene)
Gene Tree
VISTA-Point
Chr4 49.67 cM Chr4:106442329-106464329 (-)
GRCm38
OTTMUSG00000008197 (VEGA)
OTTMUSP00000008554 (VEGA)
OTTMUST00000018618 (VEGA)
rat Pcsk9 298296 (Entrez Gene)
Chr5 q34 P59996 (UniProt | EBI)
NM_199253 (RefSeq)
chimpanzee PCSK9 456880 (Entrez Gene)
Chr1 A8T644 (UniProt | EBI)
NM_001111122 (RefSeq)
rhesus macaque PCSK9 717147 (Entrez Gene)
Chr1 A8T666 (UniProt | EBI)
NM_001112660 (RefSeq)
chicken PCSK9 424664 (Entrez Gene)
Chr8 XP_003641739 (RefSeq)
zebrafish pcsk9 100150316 (Entrez Gene)
Chr20 XP_003200725 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory