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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human EPCAM HGNC:11529 (HGNC)
4072 (Entrez Gene)
185535 (OMIM)
HGNC homology
Chr2 p21 Chr2:47369148-47387028 (+)
congenital diarrhea 5 with tufting enteropathy
Lynch syndrome
P16422 (UniProt | EBI)
NM_002354 (RefSeq)
mouse Epcam MGI:106653 (MGI)
17075 (Entrez Gene)
Gene Tree
HGNC homology
Chr17 57.87 cM Chr17:87635979-87651106 (+)
congenital diarrhea 5 with tufting enteropathy
ENSMUSG00000045394 (Ensembl Gene Model)
ENSMUSP00000061935 (Ensembl)
ENSMUST00000053577 (Ensembl)
rat Epcam 171577 (Entrez Gene)
Chr6 q12 O55159 (UniProt | EBI)
NM_138541 (RefSeq)
chimpanzee EPCAM 459214 (Entrez Gene)
Chr2A XP_016803985 (RefSeq)
cattle EPCAM 514039 (Entrez Gene)
Chr11 Q3T0L5 (UniProt | EBI)
NM_001035290 (RefSeq)
dog EPCAM 481360 (Entrez Gene)
Chr10 XP_005626295 (RefSeq)
chicken EPCAM 421292 (Entrez Gene)
Chr3 Q5F381 (UniProt | EBI)
NM_001012564 (RefSeq)
zebrafish epcam 406454 (Entrez Gene)
Chr13 NP_001017593 (RefSeq)
NM_001017593 (RefSeq)
frog, western clawed epcam 496567 (Entrez Gene)
Chr5 NP_001011149 (RefSeq)
NM_001011149 (RefSeq)
macaque, rhesus EPCAM 677680 (Entrez Gene)
Chr13 Q1WER1 (UniProt | EBI)
NM_001040029 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory