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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
1744

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LRP1 HGNC:6692 (HGNC)
4035 (Entrez Gene)
107770 (OMIM)
Chr12 q13.3 Chr12:57128499-57213359 (+)
GRCh38
Q07954 (UniProt | EBI)
NM_002332 (RefSeq)
mouse Lrp1 MGI:96828 (MGI)
16971 (Entrez Gene)
Gene Tree
VISTA-Point
Chr10 74.52 cM Chr10:127538161-127621148 (-)
GRCm38
Alzheimer Disease; AD
Cerebral Amyloid Angiopathy, App-Related
Diaphragmatic Hernia, Congenital
Gastroschisis
Omphalocele, Autosomal
OTTMUSG00000031813 (VEGA)
OTTMUSP00000041991 (VEGA)
OTTMUST00000078868 (VEGA)
rat Lrp1 299858 (Entrez Gene)
Chr7 q22 NP_001123962 (RefSeq)
NM_001130490 (RefSeq)
chimpanzee LRP1 452006 (Entrez Gene)
Chr12 XP_003952220 (RefSeq)
cattle LRP1 533894 (Entrez Gene)
Chr5 XP_003582266 (RefSeq)
dog LRP1 481124 (Entrez Gene)
Chr10 XP_538245 (RefSeq)
chicken LRP1 396170 (Entrez Gene)
ChrZ P98157 (UniProt | EBI)
NM_205242 (RefSeq)
western clawed frog LOC100485788 100485788 (Entrez Gene)
ChrUN XP_002939758 (RefSeq)
zebrafish LOC565797 565797 (Entrez Gene)
Chr23 XP_001920591 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory