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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 67, Dec 12, 2012)
1736

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LIG4 HGNC:6601 (HGNC)
3981 (Entrez Gene)
601837 (OMIM)
Chr13 q33-q34 Chr13:108207442-108218368 (-)
GRCh38
LIG4 Syndrome
Myeloma, Multiple
Severe Combined Immunodeficiency with Sensitivity to Ionizing Radiation
P49917 (UniProt | EBI)
NM_002312 (RefSeq)
mouse Lig4 MGI:1335098 (MGI)
319583 (Entrez Gene)
Gene Tree
VISTA-Point
Chr8 4.52 cM Chr8:9970020-9976323 (-)
GRCm38
LIG4 Syndrome
319583 (NCBI Gene Model)
Q8BTF7 (UniProt | EBI)
NM_176953 (RefSeq)
rat Lig4 290907 (Entrez Gene)
Chr16 q12.5 NP_001099565 (RefSeq)
NM_001106095 (RefSeq)
chimpanzee LIG4 452653 (Entrez Gene)
Chr13 XP_001135359 (RefSeq)
cattle LIG4 781252 (Entrez Gene)
Chr12 NP_001178055 (RefSeq)
NM_001191126 (RefSeq)
dog LIG4 485544 (Entrez Gene)
Chr22 XP_542663 (RefSeq)
chicken LIG4 418764 (Entrez Gene)
Chr1 Q90YB1 (UniProt | EBI)
NM_001030816 (RefSeq)
zebrafish lig4 569525 (Entrez Gene)
Chr1 NP_001096593 (RefSeq)
NM_001103123 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory