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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LIG4 HGNC:6601 (HGNC)
3981 (Entrez Gene)
601837 (OMIM)
LIG4 (MyGene.info)
HGNC homology
Chr13 q33.3 Chr13:108207442-108218368 (-)
DNA ligase IV deficiency
multiple myeloma
P49917 (UniProt | EBI)
NM_001352604 (RefSeq)
mouse Lig4 MGI:1335098 (MGI)
319583 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 4.52 cM Chr8:9969049-9977686 (-)
DNA ligase IV deficiency
OTTMUSG00000059042 (VEGA)
OTTMUSP00000075448 (VEGA)
OTTMUST00000144833 (VEGA)
rat Lig4 290907 (Entrez Gene)
Chr16 q12.5 NP_001099565 (RefSeq)
NM_001106095 (RefSeq)
chimpanzee LIG4 452653 (Entrez Gene)
Chr13 XP_024204106 (RefSeq)
cattle LIG4 781252 (Entrez Gene)
Chr12 NP_001178055 (RefSeq)
NM_001191126 (RefSeq)
dog LIG4 485544 (Entrez Gene)
Chr22 XP_022263858 (RefSeq)
chicken LIG4 418764 (Entrez Gene)
Chr1 Q90YB1 (UniProt | EBI)
NM_001030816 (RefSeq)
zebrafish lig4 569525 (Entrez Gene)
Chr1 NP_001096593 (RefSeq)
NM_001103123 (RefSeq)
frog, western clawed lig4 549735 (Entrez Gene)
Chr2 NP_001016981 (RefSeq)
NM_001016981 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory