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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
1731

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LEPR HGNC:6554 (HGNC)
3953 (Entrez Gene)
601007 (OMIM)
Chr1 p31 Chr1:65420652-65637493 (+)
GRCh38
Leptin Receptor Deficiency
P48357 (UniProt | EBI)
NM_001003679 (RefSeq)
mouse Lepr MGI:104993 (MGI)
16847 (Entrez Gene)
Gene Tree
VISTA-Point
Chr4 46.96 cM Chr4:101717404-101815352 (+)
GRCm38
Diabetes Mellitus, Noninsulin-Dependent; NIDDM
Obesity
Polycystic Ovary Syndrome 1; PCOS1
OTTMUSG00000008454 (VEGA)
OTTMUSP00000008794 (VEGA)
OTTMUST00000019183 (VEGA)
rat Lepr 24536 (Entrez Gene)
Chr5 q33 Q62959 (UniProt | EBI)
NM_012596 (RefSeq)
chimpanzee LEPR 456919 (Entrez Gene)
Chr1 XP_001161897 (RefSeq)
rhesus macaque LEPR 574126 (Entrez Gene)
Chr1 Q9MYL0 (UniProt | EBI)
NM_001032819 (RefSeq)
cattle LEPR 497205 (Entrez Gene)
Chr3 q33 NP_001012285 (RefSeq)
NM_001012285 (RefSeq)
dog LEPR 450207 (Entrez Gene)
Chr5 NP_001019805 (RefSeq)
NM_001024634 (RefSeq)
chicken LEPR 374223 (Entrez Gene)
Chr8 NP_989654 (RefSeq)
NM_204323 (RefSeq)
western clawed frog lepr 724071 (Entrez Gene)
ChrUN NP_001037866 (RefSeq)
NM_001044401 (RefSeq)
zebrafish lepr 567241 (Entrez Gene)
Chr6 NP_001106847 (RefSeq)
NM_001113376 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory