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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human INS HGNC:6081 (HGNC)
3630 (Entrez Gene)
176730 (OMIM)
HGNC homology
Chr11 p15.5 Chr11:2159779-2161209 (-)
Diabetes Mellitus, Insulin-Dependent, 2
Diabetes Mellitus, Permanent Neonatal; PNDM
Maturity-Onset Diabetes of the Young, Type 10; MODY10
P01308 (UniProt | EBI)
NM_001185098 (RefSeq)
mouse Ins2 MGI:96573 (MGI)
16334 (Entrez Gene)
Gene Tree
Chr7 88.0 cM Chr7:142678656-142699510 (-)
Diabetes Mellitus, Insulin-Dependent; IDDM
Diabetes Mellitus, Noninsulin-Dependent; NIDDM
Diabetes Mellitus, Permanent Neonatal; PNDM
Maturity-Onset Diabetes of the Young; MODY
OTTMUSG00000018794 (VEGA)
OTTMUSP00000020356 (VEGA)
OTTMUST00000045252 (VEGA)
rat Ins2 24506 (Entrez Gene)
Chr1 q41 P01323 (UniProt | EBI)
NM_019130 (RefSeq)
chimpanzee INS 449570 (Entrez Gene)
Chr11 P30410 (UniProt | EBI)
NM_001008996 (RefSeq)
dog INS 483665 (Entrez Gene)
Chr18 P01321 (UniProt | EBI)
NM_001130093 (RefSeq)
chicken INS 396145 (Entrez Gene)
Chr5 P67970 (UniProt | EBI)
NM_205222 (RefSeq)
western clawed frog ins 100101718 (Entrez Gene)
ChrUN NP_001093706 (RefSeq)
NM_001100236 (RefSeq)
zebrafish ins 30262 (Entrez Gene)
Chr5 O73727 (UniProt | EBI)
NM_131056 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory