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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CFI HGNC:5394 (HGNC)
3426 (Entrez Gene)
217030 (OMIM)
Complement factor I (MyGene.info)
HGNC homology
Chr4 q25 Chr4:109731221-109802225 (-)
age related macular degeneration 13
complement factor I deficiency
hemolytic-uremic syndrome
P05156 (UniProt | EBI)
NM_001318057 (RefSeq)
mouse Cfi MGI:105937 (MGI)
12630 (Entrez Gene)
Gene Tree
HGNC homology
Chr3 59.21 cM Chr3:129835884-129875332 (+)
OTTMUSG00000054726 (VEGA)
OTTMUSP00000071761 (VEGA)
OTTMUST00000135653 (VEGA)
rat Cfi 79126 (Entrez Gene)
Chr2 q43 Q9WUW3 (UniProt | EBI)
NM_024157 (RefSeq)
chimpanzee CFI 471271 (Entrez Gene)
Chr4 XP_003310493 (RefSeq)
cattle CFI 513197 (Entrez Gene)
Chr6 NP_001033185 (RefSeq)
NM_001038096 (RefSeq)
dog CFI 478515 (Entrez Gene)
Chr32 XP_022269426 (RefSeq)
chicken CFI 428773 (Entrez Gene)
Chr4 NP_001258947 (RefSeq)
NM_001272018 (RefSeq)
zebrafish cfi 557557 (Entrez Gene)
Chr23 XP_017209949 (RefSeq)
frog, western clawed cfi 613100 (Entrez Gene)
Chr1 NP_001027508 (RefSeq)
NM_001032337 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory