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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human JUP HGNC:6207 (HGNC)
3728 (Entrez Gene)
173325 (OMIM)
Plakoglobin (MyGene.info)
HGNC homology
Chr17 q21.2 Chr17:41754607-41786853 (-)
arrhythmogenic right ventricular dysplasia 12
Naxos disease
P14923 (UniProt | EBI)
NM_001352777 (RefSeq)
mouse Jup MGI:96650 (MGI)
16480 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 63.47 cM Chr11:100368958-100397763 (-)
arrhythmogenic right ventricular dysplasia 12
epidermolytic hyperkeratosis
ENSMUSG00000001552 (Ensembl Gene Model)
ENSMUSP00000001592 (Ensembl)
ENSMUST00000001592 (Ensembl)
rat Jup 81679 (Entrez Gene)
Chr10 q31 Q6P0K8 (UniProt | EBI)
NM_031047 (RefSeq)
chimpanzee JUP 454667 (Entrez Gene)
Chr17 XP_016787314 (RefSeq)
cattle JUP 445543 (Entrez Gene)
Chr19 Q8SPJ1 (UniProt | EBI)
NM_001004024 (RefSeq)
dog JUP 480522 (Entrez Gene)
Chr9 NP_001273872 (RefSeq)
NM_001286943 (RefSeq)
chicken JUP 429710 (Entrez Gene)
Chr27 NP_001254482 (RefSeq)
NM_001267553 (RefSeq)
zebrafish jupa 30415 (Entrez Gene)
Chr11 NP_571252 (RefSeq)
NM_131177 (RefSeq)
jupb 100330886 (Entrez Gene)
Chr19 XP_021323940 (RefSeq)
frog, western clawed jup 395011 (Entrez Gene)
Chr10 NP_989380 (RefSeq)
NM_204049 (RefSeq)
macaque, rhesus JUP 707769 (Entrez Gene)
Chr16 NP_001253056 (RefSeq)
NM_001266127 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory