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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ISL1 HGNC:6132 (HGNC)
3670 (Entrez Gene)
600366 (OMIM)
ISL1 (MyGene.info)
HGNC homology
Chr5 q11.1 Chr5:51383124-51394730 (+)
P61371 (UniProt | EBI)
NM_002202 (RefSeq)
mouse Isl1 MGI:101791 (MGI)
16392 (Entrez Gene)
Gene Tree
HGNC homology
Chr13 64.87 cM Chr13:116298281-116309689 (-)
OTTMUSG00000039739 (VEGA)
OTTMUSP00000057705 (VEGA)
OTTMUST00000103329 (VEGA)
rat Isl1 64444 (Entrez Gene)
Chr2 q14 P61374 (UniProt | EBI)
NM_017339 (RefSeq)
chimpanzee ISL1 461881 (Entrez Gene)
Chr5 XP_001150633 (RefSeq)
cattle ISL1 614040 (Entrez Gene)
Chr20 NP_001092600 (RefSeq)
NM_001099130 (RefSeq)
dog ISL1 612954 (Entrez Gene)
Chr4 XP_853721 (RefSeq)
chicken ISL1 396383 (Entrez Gene)
ChrZ P50211 (UniProt | EBI)
NM_205414 (RefSeq)
zebrafish isl1 30147 (Entrez Gene)
Chr5 P53405 (UniProt | EBI)
NM_130962 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory