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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human IRF1 HGNC:6116 (HGNC)
3659 (Entrez Gene)
147575 (OMIM)
IRF1 (MyGene.info)
HGNC homology
Chr5 q31.1 Chr5:132481609-132490789 (-)
lung cancer
stomach cancer
P10914 (UniProt | EBI)
NM_001354924 (RefSeq)
mouse Irf1 MGI:96590 (MGI)
16362 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 32.0 cM Chr11:53770014-53778374 (+)
16362 (NCBI Gene Model)
P15314 (UniProt | EBI)
NM_008390 (RefSeq)
rat Irf1 24508 (Entrez Gene)
Chr10 q22 P23570 (UniProt | EBI)
NM_012591 (RefSeq)
chimpanzee IRF1 745042 (Entrez Gene)
cattle IRF1 789216 (Entrez Gene)
Chr7 Q3SZP0 (UniProt | EBI)
NM_001191261 (RefSeq)
dog IRF1 100855872 (Entrez Gene)
Chr11 XP_003639416 (RefSeq)
chicken IRF1 396384 (Entrez Gene)
Chr13 Q90876 (UniProt | EBI)
NM_205415 (RefSeq)
zebrafish irf1b 792160 (Entrez Gene)
Chr21 NP_991310 (RefSeq)
NM_205747 (RefSeq)
frog, western clawed irf1 448320 (Entrez Gene)
Chr3 NP_001006695 (RefSeq)
NM_001006694 (RefSeq)
macaque, rhesus IRF1 707788 (Entrez Gene)
Chr6 NP_001253326 (RefSeq)
NM_001266397 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory