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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
1629

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human IRF8 HGNC:5358 (HGNC)
3394 (Entrez Gene)
601565 (OMIM)
Chr16 q24.1 Chr16:85899168-85922606 (+)
GRCh38
Immunodeficiency 32a; IMD32A
Monocyte and Dendritic Cell Deficiency, Autosomal Recessive
Q02556 (UniProt | EBI)
NM_002163 (RefSeq)
mouse Irf8 MGI:96395 (MGI)
15900 (Entrez Gene)
Gene Tree
VISTA-Point
Chr8 70.05 cM Chr8:120736358-120756694 (+)
GRCm38
Myelocytic Leukemia-Like Syndrome, Familial, Chronic
OTTMUSG00000033858 (VEGA)
OTTMUSP00000046087 (VEGA)
OTTMUST00000085321 (VEGA)
rat Irf8 292060 (Entrez Gene)
Chr19 q12 NP_001008722 (RefSeq)
NM_001008722 (RefSeq)
chimpanzee IRF8 454294 (Entrez Gene)
Chr16 XP_511152 (RefSeq)
rhesus macaque IRF8 693933 (Entrez Gene)
Chr20 NP_001252887 (RefSeq)
NM_001265958 (RefSeq)
cattle IRF8 614909 (Entrez Gene)
Chr18 NP_001077238 (RefSeq)
NM_001083769 (RefSeq)
dog IRF8 489673 (Entrez Gene)
Chr5 XP_546793 (RefSeq)
chicken IRF8 396385 (Entrez Gene)
Chr11 Q90871 (UniProt | EBI)
NM_205416 (RefSeq)
western clawed frog irf8 100496217 (Entrez Gene)
ChrUN XP_002934991 (RefSeq)
zebrafish irf8 436895 (Entrez Gene)
Chr18 NP_001002622 (RefSeq)
NM_001002622 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory